Reshma Kewalramani

Reshma Kewalramani

CEO & President

Boston, US

Profile Verified by The Marque

Last Updated: 22 Sep 2026

In Their Own Right

Biography

Reshma Kewalramani is the CEO and President of Vertex Pharmaceuticals. A highly experienced medical doctor, clinician, researcher and nephrologist, she is well equipped to lead Vertex to its next stage of growth.

She previously held the positions of Executive Vice President, Chief Medical Officer and Senior Vice President. During her time at Vertex, the company has pioneered ground-breaking medical treatments for cystic fibrosis, namely SYMDEKO/SYMKEVI and TRIKAFTA/KAFTRIO, bringing these transformative new therapies to the majority of CF patients around the world.

Formerly, Dr. Kewalramani spent more than 12 years at Amgen in several senior roles, notably as Vice President, Head US Medical Organization. During this time, she expanded Amgen’s Research and Development unit and established the US Medical Organization which oversaw molecular responsibilities.

A passionate doctor, teacher, mentor, philanthropist and STEM advocate, Dr. Kewalramani is active in her community. Amongst many of her other roles and responsibilities, she is a Fellow of the American Society of Nephrology, a board member of the Biomedical Science Careers Program, a member of the Dean’s Advisory Committee at Boston University Medical School, and a board member of RIZE Massachusetts.

Dr. Kewalramani completed her internship and residency at several Mass General Brigham medical centers, including as Resident Physician at Massachusetts General Hospital.

Throughout her notable career, she has earned several accolades, earlier as a leading CEO of a Fortune 500 biotech company and as an International Institute of New England Golden Door Award Honoree. She was most recently recognised on The Time 100 Most Influential People in 2025.

She is an alumnus of Harvard Business School and holds a Summa Cum Laude medical degree from Boston University School of Medicine.

The Record

Background

  • 2020 — Present

    CEO & President

    Vertex Pharmaceuticals

    Vertex Pharmaceuticals is a leading biotechnology company that invests in scientific innovation to create transformative new medicines. Dr. Kewalramani previously served as the Chief Medical Officer and Executive Vice President of Global Medicines Development and Medical Affairs from April 2018 through March 2020.

  • Present

    Physician

    Massachusetts Eye and Ear Infirmary

    One of the top centers in the United States for ear and eye treatment. The medical facility is part of the Mass General Brigham integrated health care system.

  • Present

    Physician

    MIT - Massachusetts Institute of Technology

    She worked as a physician at MIT involved in research in the co-stimulatory field.

  • 1998 — 2001

    Resident Physician

    Massachusetts General Hospital

    One of the top-ranked hospitals in the United States, delivering on life-affirming health care and research and development that serves the community.

  • 2001 — 2002

    Nephrology Fellow

    Mass General Brigham

    Mass General Brigham is a group of medical centers and facilities in the United States with a focus on research and development and excellence in patient treatment and care.

  • 2002 — 2004

    Nephrologist and Research Fellow

    Brigham and Women's Hospital

    A leading healthcare facility in the Greater Boston Area, the Brigham and Women's Hospital treats all patients in the facility and on an outpatient basis.

  • 2004 — 2017

    Vice President, Head US Medical Organization

    Amgen

    Dr. Kewalramani gained experience in several roles at Amgen, notably, Vice President, Head US Medical Organization; Vice Present, Head Nephrology and Metabolic Therapeutic Area, Global Clinical Development; and other various roles across Global Clinical Development and Medical Affairs.

In The News

Newsfeed

  • 26 February 2026 · Time Magazine

    Physician-Scientist Reshma Kewalramani Runs One of Biotech’s Biggest Companies

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  • 16 April 2025 · Time Magazine

    100 Most Influential People of 2025: Reshma Kewalramani

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  • 21 June 2024 · Barron's

    Reshma Kewalramani Is Guiding Vertex Pharmaceuticals to Its Next Big Thing

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  • 15 March 2024 · Statnews

    Stat Status List 2024: Reshma Kewalramani

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  • 15 February 2024 · City of Boston

    Mayor Wu Awards $4.7 Million in Funding to Develop Boston's Life Sciences Workforce

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  • 18 December 2023 · Morningstar

    Vertex to Present at the 42nd Annual J.P. Morgan Healthcare Conference on January 8

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  • 8 December 2023 · The Daily Mail

    FDA approves world-first gene editing treatment: Sickle cell therapy gives hope to 100,000 Americans

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  • 16 November 2023 · Good Word News

    UK approves Vertex and CRISPR therapy for sickle cell disease and beta thalassemia in world first

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  • 3 November 2023 · The Boston Globe

    How a career pivot catapulted Vertex’s CEO to the top of the biotech world

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  • 5 October 2023 · Boston University Medical Campus

    Vertex CEO Reshma Kewalramani, MD’98, Receives 2023 Distinguished Alumni Award

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  • 20 July 2023 · Boston Business Journal

    CEO social leadership award, best corporate-nonprofit partnerships named

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  • 15 May 2023 · Yahoo! Finance

    Babson College Commencement Ceremonies Celebrate the Class of 2023

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  • 2 May 2023 · Babson College

    On Taking Risks and the Relentless Pursuit of Innovation

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  • 1 May 2023 · India New England News

    AIF Boston Gala Raises Over $1.1M, Honors Vertex & CRISPR CEOs Reshma Kewalramani & Samarth Kulkarni

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  • 21 April 2023 · Harvard Business School

    Harvard Business School Honors Five Graduates with 2023 Alumni Achievement Award

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  • 31 March 2023 · India New England News

    AIF to Honor Life Sciences Icons Reshma Kewalramani and Samarth Kulkarni

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  • 22 September 2022 · Asian American Business Development Center

    21st Anniversary of Outstanding 50 Asian Americans in Business Award

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  • 11 July 2022 · Businesswire

    Vertex to Acquire ViaCyte, Goal of Accelerating its Potentially Curative VX-880 Diabetes Programs

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  • 17 May 2022

    Vertex Announces $50 Million Commitment to Health Equity With Three Initial Grants

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  • 11 April 2022 · PharmExec

    Diversity in Action: Q&A With Reshma Kewalramani

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  • 4 April 2022 · CNBC

    Vertex Pharma sees positive results in Phase 2 trials of new non-opioid pain killer

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Formative Years

Education

  • Boston University School of Medicine

    Doctor of Medicine (M.D)/ Summa Cum Laude

    1990 — 1998

  • Boston University

    Liberal Arts/Medical Education Program; Doctor of Medicine (M.D)

    1990 — 1998

  • Harvard Business School Executive Education

    Training and Management

Areas Of Focus

Expertise

  • Philanthropy
  • Biotechnology
  • Education
  • Healthcare
  • Medical Consultant/Surgeon
  • Medicine & Clinical Research
  • Mental Health
  • Mentor
  • Pharmaceuticals